Table 3 Tools used for assessing OIPN

Current tools used for the clinical diagnosis of OIPN

National Cancer Institute-Common Toxicity Criteria (NCI-CTC)

[23]

Total Neuropathy Score clinical version (TNSc)

[24]

Modified Inflammatory Neuropathy Cause and Treatment (INCAT) group sensory sum score (mISS)

[25]

European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30

[27]

CIPN (chemotherapy induced peripheral neuropathy) 20 quality-of-life measures

[26]

Skin biopsy and quantified intraepidermal nerve fiber density

[28, 29]

LDI technology

[22]

Surface electromyography recording

[30]

Comments for the ideal CIPN assessment tools

Specific to CIPN; validated in different types of chemotherapy; easy for patients to understand and complete; can be used in postal questionnaires as well as face to face; performs consistently in different settings; requires minimal training in use and scoring; sensitive to change; detects CIPN early; and reliable with minimal interrater variability

[2]