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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Chlorpromazine induces cytotoxic autophagy in glioblastoma cells via endoplasmic reticulum stress and unfolded protein response

Fig. 6

CPZ induces mitotic catastrophe. Nuclear aberrations in control (CTL) or CPZ-treated T98G, U-87 MG and U-251 MG anchorage-dependent GBM cells (A) and TS#1, TS#83 and TS#163 neurospheres (B). Nuclei are stained in blue (Hoechst), while α-tubulin is highlighted in red and merge is the overlap of the two stainings. Aberrant nuclei are evident in all CPZ-treated GBM cells

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