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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: BH3-mimetics: recent developments in cancer therapy

Fig. 3

Co-crystal structure of Bcl-xL and small-molecule inhibitor ABT-737. The interaction of alpha-helices (H) 1-9 from Bcl-xL (pink), in combination with ABT-737 (stick diagram) are highlighted in the presence of a chloride ion (green circle) and glycerol (unlabeled lower stick) in the left panel. Bcl-xL α-helices 2-5 (H2-H5) are highlighted in pink and yellow (middle panel) and in the right panel, are shown when viewed from above

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