Table 3 The single and combined synergizing effects of ABT-737 on cell line viability and/or apoptosis

AML

ex-vivo samples

5-azacytidine

synergized

–

[112]

Breast

MDA-MB-231R

irradiation

synergized

–

[113]

Breast

T47D

cisplatin

synergized

synergized

[114]

Breast

MCF-7, ZR-75-1, MDA-MB231

irradiation

synergized

–

[35]

Breast

MDA-MB-435S

VX-680

synergized

–

[115]

Breast (TN)

MDA-MB-231

docetaxel

synergized

–

[116]

CRC

C26, HCT116, LS174T

oxaliplatin

synergized

–

[117]

CRC

HT-29, HCT116

celecoxib

synergized

–

[118]

Glioma

LN229, LN18

bortezomib

synergized

–

[119]

HNSCC

UM-22A, UM-22B, 1483

cisplatin/etopiside

synergized

–

[120]

Lung

A549 and H460 lines

perifosine

synergized

synergized

[121]

Lung

A549 and 95-D

nedaplatin

synergized

–

[106]

Leukaemia

HL-60, U-937, ML-1, MOLT-4

-single-

reduced

–

[122]

Leukaemia (T-cell)

MOLT-4

resveratrol

synergized

–

[123]

Leukaemia

HL-60

doxorubicin

synergized

–

[124]

Liver

HuH-7, HepG2, BEL-7402, SMMC-7721

norcantharidin

synergized

–

[111]

Liver

HepG2

curcumin

synergized

–

[125]

Melanoma

A375, WM852c

bortezomib

synergized

synergized

[109]

NSCLC

A549, H460, H1299, H358, H2009, H1703, H596

cisplatin

–

synergized

[126]

Oral

MC-3, HSC-3

sorafenib

synergized

–

[127]

Osteosarcoma

U-2OS

cisplatin

synergized

–

[128]

Ovarian/Gastric

SKOV-3, OVCAR-8, SGC-7901

epothilone B

synergized

–

[129]

Ovarian

patient derived organoids

naftopidil

synergized

–

[130]

Ovarian

Ovcar-3, Igrov-1

pitavastatin

synergized

–

[131]

Ovarian

A2780, cisA2780, IGROV-1, OVCAR, SK-OV-03, primary and xenograft

carboplatin

synergized

synergized

[132, 133]

Prostate

DU 145, LNCaP and PC-3

ARC

synergized

–

[107]

Renal

PV10, KRC/Y,A498, ACHN

TRAIL

synergized

–

[134]

Retinoblastoma

Y79, WERI-Rb

-single-

–

–

[108]

Thyroid

FTC236, ML1, SW1736, HTh7

doxorubicin/gemcitabine

synergized

–

[135]

Uterine/Cervical

SiHa, CaSki

irradiation

synergized

–

[136]

Breast, Colon, Liver, Pancreatic

SW480 and LIM1215, Huh-7 and HepG2, HPAC, MDA-MB-231

ARC

synergized

synergized

[137]

Breast, Colon, Prostate

MDA-MB-231, HT-29, DU145

methylseleninic acid

synergized

–

[110]