Fig. 7

SNHG17 exerts its carcinogenic role in CRC through PES1 and FOSL2. a, b CCK-8 assays were used to detect the rescuing effects of SNHG17 overexpression on cell proliferation ability in PES1 (a)- or FOSL2 (b)-silenced HCT116 cells. c, d Colony formation assays were used to detect the rescuing effects of SNHG17 overexpression on colony formation ability in PES1 (c)- or FOSL2 (d)-silenced HCT116 cells. e, f Transwell assays were performed to evaluate the rescuing effects of SNHG17 overexpression on cell migration in PES1 (e)- or FOSL2 (f)-silenced HCT116 cells. g Integrated model depicting the oncogenic effects and mechanism of SNHG17 in terms of CRC growth and metastasis.