Heterogeneity of BCSCs contributes to the metastatic organotropism of breast cancer

Table 2 Metastatic organotropism and BCSCs features in different molecular subtypes of breast cancer

Molecular subtype	Metastatic organotropism	Features of BCSCs
Molecular subtype	Metastatic organotropism	Proportion	Molecular marker	Epithelial / Mesenchymal status
Luminal A	Bone [33]	Low	-	-
Luminal B	Bone, Liver [33, 34]	Low	-	-
HER2 enriched	Lung, Brain, Liver [33]	High	ALDH+ [35,36,37]	Epithelial-like
Triple negative	Lung, Brain, Distant nodes [33]	High	CD24- CD44+ [35, 38, 39]	Mesenchymal-like [40]

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