Fig. 3

LINC00460 promotes CRC cell migration, invasion and supports the proper function of the EMT transcription program and the location of LINC00460 in CRC cells. a, b, c, d The ability of migration and invasion in HCT116 and SW480 cells ± LINC00460 KD/OE (***p < 0.001). e, f, g, h Relative mRNA expression levels of LINC00460 and EMT markers in HCT116 and SW480 cells ± LINC00460 KD/OE. The relative mRNA expression levels were normalized to GAPDH (*p < 0.05, **p < 0.01, ***p < 0.001). i, j Western blots of EMT markers in HCT116 and SW620 cells ± LINC00460 KD/OE. GAPDH was used as a loading control