Fig. 5

Long-term LNT treatments induce regression of LAP0297 lung cancer. LAP0297 lung cancer-bearing mice were prepared as described in Fig. 1. When tumors reached 4 × 4 mm in diameter, mice were randomly divided into 2 groups and received i.p. injection of saline or LNT (1.0 mg/kg) for 1 month. a Representative photographs of LAP0297 lung cancer-bearing mice in saline and LNT-treated group were taken at the end of the experiment. b The growth curves of LAP0297 lung cancer upon long-term therapy of saline or LNT. c The percentage of tumor-bearing mice on day 45 after tumor inoculation (NS group, n = 17 mice, LNT-treated group, n = 24 mice). *** p < 0.001