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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Circ_0000658 knockdown inhibits epithelial-mesenchymal transition in bladder cancer via miR-498-induced HMGA2 downregulation

Fig. 3

Circ_0000658 promotes the oncogenic phenotypes of BCa cells. A The expression of circ_0000658 and EMT markers β-catenin, E-cadherin, N-cadherin, Slug, Snail, ZEB1 and Twist in T24 cells determined with RT-qPCR; B The expression of circ_0000658 and EMT markers β-catenin, E-cadherin, N-cadherin, Slug, Snail, ZEB1 and Twist in 5637 cells determined with RT-qPCR; C The expression of circ_0000658 and EMT markers β-catenin, E-cadherin, N-cadherin, Slug, Snail, ZEB1 and Twist in T24 and 5637 cells determined with Western blot analysis; D The cell migration ability of T24 and 5637 cells measured with scratch test. E The cell proliferation of T24 and 5637 cells after circ_0000658 silencing determined with EdU assay; F The cell invasion of T24 and 5637 cells determined with Transwell assay. *p < 0.05 vs. oe-NC; #p < 0.05 vs. sh-NC. All cell experiments were repeated three times

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