Fig. 6
From: Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy
DAC sensitizes GBC cells to gemcitabine in vivo. a Experiment timeline and dosing schedule for xenograft models. b Western blot for ELP5 protein levels in NOZ xenograft tumours undergoing different treatments. c Tumour growth curves in NOZ xenograft models. d Statistical analysis of tumour weight in NOZ xenograft tumours after scarification. e Representative images of NOZ xenograft tumours after scarification. f Tumour growth curves in GBC-SD xenograft models. g Statistical analysis of tumour weight in GBC-SD xenograft tumours after scarification. h Representative images of GBC-SD xenograft tumours after scarification. i Representative immunohistochemistry of ELP5 proteins in paraffin-fixed NOZ xenograft tissues. Scale bar = 100 μm. One-way ANOVA test for statistical analysis, ns, not significant, **P < 0.01, ***P < 0.001