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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Correction to: USP13 functions as a tumor suppressor by blocking the NF-kB-mediated PTEN downregulation in human bladder cancer

Fig. 2

The biological function of miR-130b/301b and USP13 in vitro. Cell proliferative capacity was measured by Cell Counting-Kit 8 (CCK-8) (a and b) assay and colony formation assay (e) in miR-130b/301b overexpressed 5637 and UM-UC-3 cells. CCK-8 (c and d) and colony formation assay (f) were also performed to evaluate the cellular proliferation in USP13 knocked down 5637 and UM-UC-3 cells. Cell invasive and migrative capacities were measured by transwell assay in miR-130b/301b overexpressed (g and h) or USP13 knocked down (i and j) 5637 and UM-UC-3 cells. Cell proliferation was detected by CCK-8 (k) and colony formation assay (l) in USP13 knocked down alone or USP13 knocked down as well as PTEN expression restored 5637 and UM-UC-3 cells. Cell invasive (m) and migrative (n) capacities were measured by Transwell assay in USP13 knocked down alone or USP13 knocked down as well as PTEN expression restored 5637 and UM-UC-3 cells. Original magnification: 400×. *P < 0.05 and **P < 0.01, as determined by Student’s T-test

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