Fig. 6

High PTEN levels correlate with USP13 overexpression in a subset of human bladder cancer tissue specimens. a. Representative images demonstrating PTEN and USP13 immunohistochemistry (IHC) staining of human bladder cancer tissue specimens from 30 bladder cancer patients. b. Quantification of PTEN or USP13 staining in BC tissue specimens. Staining intensity of PTEN or USP13 was scored as 0 to3 (0: no staining, 1: weak staining, 2: medium staining, and 3: strong staining. 0 and 1 were classified as low-expression, whereas 2 and 3 were defined as high-expression. High PTEN expression was correlated with high USP13 expression (P < 0.05, Fisher’s exact test)