Fig. 2
From: Loss of epidermal MCPIP1 is associated with aggressive squamous cell carcinoma
DMBA/TPA-induced epidermal papillomas in Mcpip1eKO mice. (a) Schematic diagram showing the timeline of the DMBA/TPA skin carcinogenesis protocol. (b) Tumor incidence (percentage of mice with papillomas), n = 11 mice. (c) Tumor multiplicity (average number of papillomas per mouse). (d) Mean tumor volume per mouse. Individual tumor volumes were calculated based on the following equation: volume [mm3] = (weight2 × height) / 2. The data are shown as the mean ± SEM values; n = 9-10. Multiple samples t-test was used to calculate P-values. *P < 0.05, **P < 0.01. (e) Dorsal view of mice at 10-12 weeks after DMBA treatment. The black arrowheads indicate exophytic papillomas, and the white arrowheads indicate endophytic papillomas