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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: RNA binding protein HuD promotes autophagy and tumor stress survival by suppressing mTORC1 activity and augmenting ARL6IP1 levels

Fig. 3

HuD and pS6 levels in neuroblastoma tumors. A Protein expression comparison of HuD and pS6K in IMR-32 xenograft tumor samples; yellow scale bar corresponds to 50 μm and white scale bar corresponds to 5 μm. B Protein expression comparison of HuD and Ki67 in IMR-32 xenograft tumor samples; yellow scale bar corresponds to 50 μm and white scale bar corresponds to 5 μm. C Expression comparison of HuD and pS6K in 5 neuroblastoma patients; scale bar corresponds to 200 μm. D Expression comparison of HuD and pS6K in IMR-32 xenograft tumor samples (control vs. silenced HuD) (refer to Fig. 8B, C and E, for the IMR-32 xenograft tumor growth, volume and weight changes). Scale bar corresponds to 50 μm and relative quantifications for “B” shown. Data are presented as mean ± SEM; t-test: *p < 0.05, **p < 0.01, ***p < 0.001

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