Fig. 2

Comparison of morphological changes in A549 and H1299 cells cultured in hEML-CM and T-CM. a Morphology of A549 cultured in T-CM. b Morphology of A549 cultured in hEML-CM. Images were obtained with a phase-contrast microscope. c Ultrastructure of A549 cultured in T-CM, the cytoplasm contains densely stained lamellar bodies (arrows) inset shows detail of lamellar bodies. d Ultrastructure of A549 cultured in hEML-CM, shows spindled cell with cytoplasmatic filaments (arrows) and dilated rough endoplasmic reticulum (dotted arrow) inset shows detail of like fibronexus structure (asterisk). e Morphology of H1299 cultured in T-CM. f Morphology of H1299 cultured in hEML-CM. Images were obtained with a phase-contrast microscope. g Ultrastructure of H1299 cultured in T-CM, showing cytoplasmatic electron-dense lipid structures (arrows). h Ultrastructure of H1299 cultured in hEML-CM