Fig. 5

MiR-23a-3p suppressed sorafenib-induced ferroptosis. A Dot plot showing KEGG pathway enrichment for differentially expressed proteins among NC + sorafenib, NC, and miR-23a-3p groups. B Heatmap showing protein expression pattern with KEGG pathway annotation. C The protein expression of GPX4 and ACSL4. D Chelatable iron accumulation was detected by fluorescent indicator Phen Green SK with dynamic quenching signals. E The deposition of lipid peroxides was stained with BODIPY and measured by LSM780 confocal imaging. F Cell viability of HCC cells examined by MTT assay