Fig. 2
ERRα elevated unsaturated fatty acid (UFA)-containing GPs in EC (A) Seven subgroups of lipids in KLE cells are detected using lipidomics. (B) 36 classes of lipids were tested in KLE cells. (C) Systematic lipidomic changes between KLE and KLETFEB−OV assessed by orthogonal partial least squares-discriminant analysis (OPLS-DA). (D) Systematic lipidomic changes between KLE and KLEERRα−OV assessed by OPLS-DA. (E) Significant lipid species associated with TFEB and its PC/SM evaluation. (F-G) Significant lipid species associated with ERRα and its PC/SM evaluation. (p < 0.05 and VIP > 1 indicate significant). *, p < 0.05. Statistical tests: Student’ s t-test. TFEB-OV: TFEB Over-Expressed; ERRα-OV: ERRα Over-Expressed.