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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Lipid reprogramming induced by the TFEB-ERRα axis enhanced membrane fluidity to promote EC progression

Fig. 6

High expression of TFEB-ERRα is associated with dyslipidemia and metastasis in EC patients The immunohistochemical expression of several proteins and their correlations are shown. (A) The immunohistochemical expression of TFEB and ERRα in the normal endometrium (n = 32) and EC at different FIGO stages (n = 79) (magnification: × 400). (B) The correlation between TFEB and ERRα expression is shown in tissues. (C) Analysis of TFEB-ERRα and clinicopathological features. (D) The differences level of serum TG, HDL, APOA and LDL in groups with different expression levels of TFEB. *, p < 0.05. Statistical tests: Student’s t-test (D), pearson’s rank correlation analysis (C). MI: Myometrial Invasion; LNM: Lymph Node Metastases; TG: Triglyceride; HDL: High-Density Lipoprotein; APOA: Apolipoprotein A; LDL: Low-Density Lipoprotein.

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