Fig. 1
INPP5F expression is elevated in HCC and associated with poor clinical outcome. A HCC datasets from Oncomine database (https://www.oncomine.org) showed increase of INPP5F mRNA in HCC samples. B Analysis of TCGA-HCC dataset (http://gepia.cancer-pku.cn) confirmed the increase of INPP5F mRNA in HCC samples. C Subgroups analysis of the Wurmbach-HCC cohort (https://www.oncomine.org) exhibitd higher mRNA expression level of INPP5F in HCC patients with worse histological differentiation grade and satellite lesions. D Kaplan-Meier analysis of the overall survival using the TCGA-LIHC cohort according to INPP5F expression . E The mRNA levels of INPP5F in 88 pairs of HCC and adjacent non-tumor tissues were measured by QRT-PCR. F The protein levels of INPP5F in 6 pairs of HCC and adjacent non-tumor tissues were measured by Western blot. G The expression of INPP5F in 232 pairs of HCC and adjacent non-tumor tissues was detected by IHC. H The clinical significance of INPP5F expression in overall survival was confirmed in SYSMH-HCC cohort by Kaplan-Meier survival analysis. ALL *P < 0.05, **P < 0.01, ***P < 0.001. Scale bar: 100 um