Fig. 3

INPP5F facilitates HCC tumor growth in vivo. Six nude mice were used in subcutaneous xenograft model per group. A Representative images of subcutaneous xenograft model using INPP5F stable knockdown MHCC-97H and its control cells. B Tumors derived from the subcutaneous xenograft model in both groups. C The tumor weight in both groups was compared. D The tumor volumes were measured every week and indicated by curves. E H&E, INPP5F and Ki67 staining were conducted in serial sections of tumors from both groups. F Three NOD/SCID mice were used in orthotopic xenograft model per group to further evaluate the effect of INPP5F on cell growth in vivo. All *P < 0.05. Scale bar: 100 um