Fig. 8From: INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinomaModel for the mechanism of INPP5F in facilitating HCC tumor growth. INPP5F translocates into cytoplasm by binding with CRM1, where INPP5F interacts with ASPH and activates Notch-c-MYC/cyclin E1 pathway, resulting in enhancement of HCC cell aerobic glycolysis and proliferationBack to article page