Skip to main content
Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Targeting ZFP64/GAL-1 axis promotes therapeutic effect of nab-paclitaxel and reverses immunosuppressive microenvironment in gastric cancer

Fig. 2

ZFP64 promotes GC cell migration and invasion in vitro. A-B The ZFP64 mRNA and protein level were detected in various GC cell lines. C-D Successful knockdown of ZFP64 in AGS cells and overexpression of ZFP64 in MGC-803 and HGC-27 cells. E-F The migration and invasion of AGS parental cells were compared with ZFP64 knockdown cells; the migration and invasion of MGC-803 or HGC-27 parental cells were compared with ZFP64-overexpressing cells. G-H The expression of EMT-related proteins was analyzed in ZFP64 knockdown or overexpressing cells using western blotting and immunofluorescence staining. All experiments were repeated at least 3 times. EMT, epithelial-mesenchymal transition; qRT-PCR, quantitative PCR with reverse transcription. ** P < 0.01, *** P < 0.005, and **** P < 0.001

Back to article page