Fig. 6From: Loss of RPS27a expression regulates the cell cycle, apoptosis, and proliferation via the RPL11-MDM2-p53 pathway in lung adenocarcinoma cellsHigh levels of RPS27a correlate with LUAD progression and poorer prognosis. A, B Comparison of RPS27a mRNA expression between normal lung tissues and tumor tissues with LUAD from TCGA datasets. *p < 0.05, **p < 0.01 were calculated with ANOVA. C The expression of RPS27a mRNA in LUAD types at different stages (http://gepia.cancer-pku.cn/). D, E Kaplan-Meier curves estimating overall survival (D) and disease-free survival (E) in patients with low and high expression levels of RPS27a mRNA in LUAD from the TCGA datasets. Log-rank test, p < 0.001. F The survival in patients with low and high expression levels of RPS27a mRNA in LUAD from GEO datasets. G-I The correlation analysis of RPS27a mRNA expression between other genes in patients with LUAD from TCGA datasets using Pearson’s correlation coefficient. The expression of mRNA was converted to log value and the scatter plot was drawn by the Ggplot-R software LUAD, lung adenocarcinomaBack to article page