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Fig. 9 | Journal of Experimental & Clinical Cancer Research

Fig. 9

From: Reactive oxygen species reprogram macrophages to suppress antitumor immune response through the exosomal miR-155-5p/PD-L1 pathway

Fig. 9

Graphic abstract. High level of ROS in cancer cells decrease tumor exosomal miR-155-5p that is taken up by macrophages to create an immunosuppressive microenvironment by upregulation of PD-L1 and other immunosuppressive factors that foster ovarian cancer development. Increase of tumor exo-miR-155 prevents ROS-mediated suppressive tumor immune response in ovarian cancer

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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