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Table 1 Correlation between FTO expression and clinicopathological features in patients with PTC (n = 100)

From: FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mRNA in an N6-methyladenosine-dependent manner

Characteristic

n

FTO

P value

High expression (%)

Low expression (%)

Gender

 Male

33

14 (42.4)

19 (57.6)

0.229

 Female

67

37 (55.2)

30 (44.8)

 

Age (Years)

  < 55

41

25 (61.0)

16 (39.0)

0.096

  ≥ 55

59

26 (44.1)

33 (55.9)

 

Tumor size (cm)

  < 2

47

28 (59.6)

19 (40.4)

0.106

  ≥ 2

53

23 (43.4)

30 (56.6)

 

Extrathyroidal invasion

 Yes

33

10 (30.3)

23 (69.7)

0.004*

 No

67

41 (61.2)

26 (38.8)

 

Lymph node metastasis

 Yes

72

32 (44.4)

40 (55.6)

0.035*

 No

28

19 (67.9)

9 (32.1)

 

TNM stage

 I-II

85

45 (52.9)

40 (47.1)

0.355

 III-IV

15

6 (40.0)

9 (60.0)

 
  1. *P < 0.05