Fig. 4
From: CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma
T22-PE24-H6 and T22-DITOX-H6 antitumor effect in a CXCR4+ HNSCC subcutaneous mouse model. A) Schematic representation of the experimental design followed in this study. B Variation of the tumor volume in each group (buffer, T22-PE24-H6, and T22-DITOX-H6) in the time course of the experiment. C Tumor weight registered at the end point of the experiment for the three experimental groups. D Body weight of buffer, T22-PE24-H6, and T22-DITOX-H6 treated animals along the study. * p < 0.05; ** p < 0.01; *** p < 0.001; n = 10 per group (total animal number 30). Statistical analysis performed by Student t-test. Error bars indicate SEM