Fig. 7
From: CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma
GSDME expression levels in HNSCC patient samples. A GSDME expression analysis by western blotting in two patient derived tumor samples (909 and 575) maintained in vitro. Phase-contrast imaging of 909 and 575 cultures showing their morphology (magnification 400x). B Representative IHC images of GSDME expression in HNSCC patient tumor samples presenting different levels of expression. C Representative IHC images of CXCR4 receptor expression in patient tumor samples. D Percentage of CXCR4 and GSDME positive and negative stained samples in the HNSCC patient cohort. Percentage of GSDME+ samples that were also positive for CXCR4 IHC. Scale bars = 200 μm