Skip to main content
Fig. 9 | Journal of Experimental & Clinical Cancer Research

Fig. 9

From: Colorectal cancer development is affected by the ECM molecule EMILIN-2 hinging on macrophage polarization via the TLR-4/MyD88 pathway

Fig. 9

Loss of EMILIN-2 associates with low CD86 and high IL4R levels. A Representative images and quantification of the immunofluorescence analyses of EMILIN-2 in the bioptic samples of the normal colonic mucosa and the adjacent neoplastic tissue. Green: EMILIN-2, red: β-catenin, Blue: nuclei. Scale bar = 50 μm. B Representative images of the immunofluorescence analyses of CD86 (green, top panel) and IL4R (green, low panel) in five patients displaying different EMILIN-2 expression levels (from high to low, as indicated). Blue: nuclei. Scale bar = 50 μm. Graph represents the mean ± SD; P values were obtained using the paired Student’s t-test; ***P < 0.001

Back to article page