Fig. 13

A Schematic illustration of the preparation of P-NPs and TAM repolarization effect of P-NPs for immune induced anticancer therapy. B Tumor volume in different groups of 4 T1 tumor-bearing mice within 14 days. **p < 0.01. C Representative images of tumor tissues were collected from different groups on the 14th day. D Body weights of mice after different treatments. E Cell viabilities of 4 T1 cancer cells treated with different concentrations of PPV-PSMA-NPs with or without irradiation (30 min, 25 mM cm^− 2). F Representative immunofluorescence staining images for CD80 (red), iNOS (red), TNFα (red), CD206 (green) and CD163 (green), as well as immunofluorescence staining observation of TUNEL staining (green) of tumor sections from different groups [172]