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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response

Fig. 4

Autophagy regulates the response of prostate cancer cells to therapy. An increasing challenge in prostate cancer therapy is therapy resistance. On the one hand, autophagy activation as a tumor-promoting factor, can inhibit apoptosis and mediate chemoresistance. On the other hand, tumor-suppressor autophagy can sensitize prostate cancer cells to chemotherapy via triggering apoptosis

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