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Table 2 Univariate Cox regression analysis of potential poor prognostic factors for HCC patients in our study

From: PPP1R26 drives hepatocellular carcinoma progression by controlling glycolysis and epithelial-mesenchymal transition

Variables

Hazard ratio (95% confidence interval)

P-value

PPP1R26

 Negative

1

 

 Positive

2.894 (1.231–6.805)

0.015

Sex

 Female

1

 

 Male

0.781 (0.332–1.836)

0.570

Age (years)

  ≤ 60

1

 

 >60

0.953 (0.519–1.75)

0.877

Tumor size (cm)

  ≤ 5

1

 

 >5

0.953 (0.519–1.75)

0.877

Tumor number

 Single

1

 

 Multiple

0.369 (0.206–0.662)

0.001

Microscopic vascular invasion

 Negative

1

 

 Positive

2.093 (1.124–3.898)

0.020

Cirrhosis

 Negative

1

 

 Positive

0.799 (0.11–5.794)

0.824

HBV

 Negative

1

 

 Positive

1.315 (0.723–2.39)

0.370

HCV

 Negative

1

 

 Positive

0.704 (0.373–1.328)

0.278

Edmondson-Steiner grade

 1,2

1

 

 3,4

3.721 (2.1–6.595)

0.000

BCLC stage

 0 or A

1

 

 B

2.794 (1.278–6.107)

0.010

 C

2.812 (1.51–5.236)

0.001

AFP (ng/ml)

  ≤ 200

1

 

 >200

2.418 (1.374–4.254)

0.002