Fig. 1
From: Inhibition of the mitochondrial protein Opa1 curtails breast cancer growth
OPA1 is overexpressed in breast cancer tissue. a TNM plot of the OPA1 expression across all tissues in available normal and tumor RNA sequencing data (n = 15,648 normal, 40,442 tumor samples, *P < 0.05). Data are resorted from https://tnmplot.com. b Violin plot of OPA1 expression in breast invasive carcinoma from RNA sequencing data available. Data are resorted from https://tnmplot.com. c OPA1 mRNA expression in breast cancer type from METABRIC data using cbioportal (n = 1904 tumors). Tumors have been classified into five molecular intrinsic subtypes: Basal-like, HER2-enriched, Luminal A, Luminal B and Normal-like using the PAM 50 signature. d Kaplan-Meier survival curve for breast cancer patients stratified according to high (Q4) or low (Q1) OPA1 levels. Data are resorted from Kaplan-Meier Plotter (http://kmplot.com). (Affymetrix id: 214306_at); n = 4934; Status: all. Follow up threshold: all