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Table 1 Correlation of IL-32 expression level with clinicopathological features in ESCC patients

From: Extracellular vesicle IL-32 promotes the M2 macrophage polarization and metastasis of esophageal squamous cell carcinoma via FAK/STAT3 pathway

Variables

All cases (N)

IL-32 expression level (IHC-score)

P valuea, b

Low, N (%)

High, N (%)

Age (year)

 < 57

15

9 (16.1)

6 (10.7)

0.905

 >=57

41

22 (39.3)

19 (33.9)

 

Gender

 Male

41

24 (42.9)

17 (30.4)

0.626

 Female

15

7 (12.5)

8 (14.3)

 

Tumor location

 Upper

9

8 (14.3)

1 (1.8)

0.087

 Middle

33

16 (28.6)

17 (30.4)

 

 Lower

14

7 (12.5)

7 (12.5)

 

Tumor differentiation

 Well

10

8 (14.3)

2 (3.6)

0.159

 Moderate

33

15 (26.8)

18 (32.1)

 

 Poor

13

7 (12.5)

6 (10.7)

 

Pathological stage

 IA-IB

9

6 (10.7)

3 (5.4)

0.304

 IIA-IIB

22

14 (25)

8 (14.3)

 

 IIIA-IIIC

25

11 (19.6)

14 (25)

 

Tumor stage

 T1-T2

24

13 (23.2)

11 (19.6)

0.265

 T3-T4

32

18 (32.1)

14 (25)

 

Nodal stage

 N0

27

18 (32.1)

9 (16.1)

0.025*

 N1

21

12 (21.4)

9 (16.1)

 

 N2-N3

8

1 (1.8)

7 (12.5)

 
  1. N Number
  2. aχ2 test to compare clinicopathological parameters in IL-32 low-expression group versus high-expression group
  3. bP < 0.05 is compared significant