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Table 3 Clinicopathological characteristics of RECI2 patients (N = 14)

From: SEMA6A/RhoA/YAP axis mediates tumor-stroma interactions and prevents response to dual BRAF/MEK inhibition in BRAF-mutant melanoma

Patient

Gender

Progression-free interval, mo

OS, mo

% of SEMA6A+ cells

SEMA6A IS

Tumor site

Short-Term Responders

 1

F

12

35

70%

2

Metastasis

 4

M

9

16

60%

2

Lung

 10

F

11

18

60%

2

Lymph node

50%

1

Lung

 13

F

4

20

60%

2

Lung and lymph node

 14

F

8

98

70%

2

Occipital fragment

 15

F

12

27

50%

1

Lung

Long-Term Responders

 2

M

Ongoing

67

68

30%

1

Middle meatus

 3

F

Ongoing

58

91

30%

1

Lymph node

 5

M

39

63

60%

2

Back

 6

M

24

50

30%

1

Lung

 7

M

60

75

30%

2

Face

 8

M

Ongoing

82

83

30%

2

Back

 9

M

48

86

30%

2

Lung

 11

F

Ongoing

75

80

30%

1

Lymph node