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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer

Fig. 1

citH3 staining is present in all endometrial tumor grades. IHC staining of endometrial FFPE tissues with anti-citH3 antibody observed by light microscopy, scale 30 um, 20 × objective. A Staining of citH3 in the leukocyte infiltrate in all EC grades (G1, G2, G3), ranging from low to high signal intensity. B Healthy subjects (HSs) are negative for the staining. C Box-plots of citH3 staining % in leucocytes infiltrate in 48 EC samples. Boxes extend from the 25th to 75th percentiles, the horizontal line in the box represent median. X indicates mean value. D Images of G2 and G3 EC tissues (40 × objective). Black arrows indicate citH3 release into the extracellular space. All scale bars indicate 30 mm

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