Fig. 5

Amount of mono- di- and tri- nucleosome cfDNA related to the total DNA increases in EC serum samples. A Schematically representation of the different DNA regions analyzed (region X, 1, 1-x, 2, total). B Box-plots of cDNA region 1 DNA content in HSs and ECs. C Box-plots of cDNA region 1 DNA content in HSs and in different EC grades (G1, G2, and G3). FU: fluorescence units (proportional to the DNA molarity/concentration), LM: low marker, HM: high marker. Boxes extend from the 25th to 75th percentiles, and the horizontal line in the box the median