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Table 1 ROC analysis. (Status = Healthy subjects vs endometrial cancer patients)

From: Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer

 

Area Under the Curve (AUC) (95%CI)

p-value

Test direction

Sensitivity

Specificity

Cut-off

cfDNA

0.838 (0.76–0.92)

 < 0.001

Higher values indicate Cancer

0.67

1.00

712.3

cfmtDNA

0.854 (0.77–0.94)

 < 0.001

Lower values indicate Cancer

0.65

0.95

16.5

citH3

0.583 (0.44–0.73)

0.339

Higher values indicate Cancer

0.33

0.93

9.2