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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: A positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression

Fig. 4

CXCL8-CXCR1/2 activated JAK/STAT1 signal pathway and promoted GC progression. A CXCL8 activated the JAK/STAT1 signal pathway. The STAT1 specific inhibitor (Fludarabine) could antagonize the effects of CXCL8. B-D Migration patterns, migration trail, and average traveled distances of GC cells treated with CXCL8 or CXCL8 and Fludarabine together. E Fludarabine limited the GC invasion. F, G CCK-8, and colony formation assay revealed that the Fludarabine could resist CXCL8’s promotion of GC proliferation

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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