Fig. 4

circ_0087429 can competitively bind with miR-5003-3p. a-b. The expression changes in candidate miRNAs after circ_0087429 overexpression or knockdown were determined by qRT-PCR. c. The differential expression of miR-5003-3p between cervical cancer and normal cervical epithelial cell lines was detected by qRT–PCR. d. The differential expression of miR-5003-3p between cervical cancer and adjacent tissue samples was detected by qRT–PCR. e. Spearman’s correlation analysis confirmed the correlation between circ_0087429 and miR-5003-3p expression in cervical cancer tissue samples. f. The colocalization of circ_0087429 and miR-5003-3p in cells was detected by FISH staining. Scale bar, 50 μm. g. The binding sites of circ_0087429 and miR-5003-3p were predicted by circBank. h-i. A luciferase reporter assay was used to examine the relative luciferase activity of the circ_0087429WT and circ_0087429MUT. **p < 0.01, ***p < 0.001, NS means no statistical significance