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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway

Fig. 1

KIF23 is overexpressed in TNBC and associated with poor prognosis. A The Venn-diagram showed the upregulated genes in TNBC. B Expression of KIF23 in 52 breast cancer cell lines from public microarray dataset (GSE41313). C Expression of KIF23 in luminal breast cancer and TNBC from public microarray dataset (GSE5460). D-E: KIF23 mRNA D and protein E expression in different subtypes of breast cancer based on TCGA and CPTAC database. F Kaplan-Meier survival analysis showed the correlation between the expression of KIF23 and the relapse free survival of TNBC patients based on TCGA. G Expression of KIF23 in the breast cancer cell lines and MCF-10A. H Expression of KIF23 in TNBC tissues and adjacent normal tissues. The relative quantification was calculated by the 2-ΔΔCt method and normalized based on GAPDH. Data were shown as mean ± SD. *p <0.05, **p <0.01, ***p<0.001

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