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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer

Fig. 2

Screening of DEGs in BLCA (A) The volcano plot shows the upregulated and downregulated DEGs in the BLCA tissues compared to normal bladder tissues from TCGA database. (B) The volcano plot shows the upregulated and downregulated DEGs in 19 pairs of BLCA samples and their matched adjacent normal tissue selected from TCGA database. (C) The volcano plot shows the upregulated and downregulated DEGs in the combined expression data from GTEx and TCGA database. (D) Venn diagram of the DEGs screened by three analytic methods, revealing 1592 intersected genes. (E) Venn diagram of the prognosis—associated genes selected by KM and Cox analyses, revealing 70 intersected genes. (F) Survival curves of patients from TCGA-BLCA database with high or low (FASN, IGFL2, PLOD1 or TEAD4) expression levels

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