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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer

Fig. 7

TEAD4 regulates the PI3K/AKT pathway in BLCA cells (A) Volcano plot of DEGs extracted by TEAD4 mRNA expression. (P < 0.05, |log2 FC|≥ 1). (B) KEGG analysis for 4522 DEGs extracted by TEAD4 mRNA expression. (C) Venn diagram of the EMT genes that are strongly correlated with TEAD4, revealing 34 intersected genes. (D) KEGG analysis for 34 genes that coexisted in the three gene sets. (E) Relative expression levels of PI3K, AKT, p-PI3K, p-AKT, TEAD4 and GAPDH in the T24 and 5637 cells transfected with LV-NC or LV-shTEAD4. (F) Relative expression levels of PI3K, AKT, p-PI3K, p-AKT, TEAD4 and GAPDH in the 5637 and TCCSUP cells transfected with Vector or OE-TEAD4 plasmid

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