Fig. 2From: Extracellular vesicle PD-L1 dynamics predict durable response to immune-checkpoint inhibitors and survival in patients with non-small cell lung cancerEVs characterization: (A) Nanoparticle tracking analysis (NTA) of EVs isolated from advanced NSCLC plasma samples showing a concentration of 2.15 × 108 particles/mL with a mode diameter of 68.4 nm. (B) The immunogold transmission electron microscopy (TEM) depicted EVs of similar size with expression of PD-L1 in the membrane. (C) Western blot (WB) images revealed expression of PD-L1, Flotillin-1, and CD9 in the plasma EVs and lung cancer culture EVs, while low expression of GM130Back to article page