Skip to main content
Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming

Fig. 3

Inflammatory and growth factor-related signaling activation in the TAA rat model of CCA. a Quantification of bacterial DNA levels in the livers of control (Veh) and TAA treated rats. *p < 0.05. b mRNA levels of Il6 and the EGFR ligands heparin-binding EGF (Hbegf), amphiregulin (Areg) and epiregulin (Ereg) in liver tissue samples from control rats (Vehicle), peritumour liver tissues and tumour tissues. *p < 0.05, **p < 0.01, ***p < 0.001. d Immunohistochemical analysis of p-ERK1/2 in liver tissue samples from control rats (Vehicle), peritumour liver tissues and tumour tissues. Representative images are shown. c Immunohistochemical analysis of p-STAT3 in liver tissue samples from control rats (Vehicle), peritumour liver tissues and tumour tissues. Representative images are shown

Back to article page

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us