Fig. 3
From: Fast detection, a precise and sensitive diagnostic agent for breast cancer
Tumor-selective imaging of NCL targeting recognition by AS1411@RuPEP nanoprobe. A The possible process of AS1411@RuPEP nanoprobe targeting recognize NCL on the cells membrane surface to selective image tumor cells. The distribution (B) and expression (C and D) of NCL in breast cancer MDA-MB-231, MCF-7 cells and human normal MCF-10A cells. The localization (E and F) of AS411@RuPEP nanoprobe in breast cancer MDA-MB-231, MCF-7 cells and human normal MCF-10A cells. G LSCM images on co-cultivation of MDA-MB-231 and MCF-10A cells in one confocal dish after incubation with 0.2 mL AS1411@RuPEP (5 μM) for 6 h. Scale bar = 20 μm. G The overlay data were analyzed using Image Pro Plus