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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC)

Fig. 2

Increased RAGE expression correlates with worse prognostic hallmarks in breast cancer. A Median Overall Survival (OS) rate in breast cancer patients harboring high and low RAGE expression levels. p-value is shown within the box. B Multivariate Cox proportional hazard model linking RAGE expression pattern to breast tumor stage, histological grade and receptor expression pattern, respectively. C Gene Expression Profiling Interactive Analysis (GEPIA) box plot of RAGE in TNBC, HER2-positive, Luminal-A and Luminal-B breast cancer subclasses. D Working hypothesis postulating the potential putative binding site of S100A8/A9 on the V-domain of RAGE

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