Fig. 2

Immune subtypes of pediatric tumors. A Spearman’s correlation of 105 cancer immune signatures. Highly correlated signatures are clustered into 5 modules (black rectangles). B Heatmap showing the enrichment of immune signatures for each patient. Tumors are clustered into 6 subtypes based on the enrichment patterns. C Distribution of the cancer types within the immune subtypes. Colors represent the cancer types. D Distribution of the immune subtypes within TARGET pediatric tumors. Colors represent the immune subtypes. E Distributions of signature scores within the six immune subtypes (rows), with dashed line indicating the median