Fig. 7

High GR, ERα, and RARα levels correlated with favorable prognosis and neuronal differentiation status in NB patients. A Kaplan-Meier overall and event free survival curves for patients divided into High^{GR + ERα} (74 patients) versus Low^{GR + ERα} (80 patients) mRNA expression levels. B mRNA expression of the neuronal differentiation markers TH, NGFR, and SCG2 in the High^{GR + ERα} versus Low^{GR + ERα} patient groups. C Kaplan-Meier overall survival curves for patients divided into four patient groups according to MYCN status. MNA High^GR + ER (0 patients) versus Low^{GR + ERα + RARα} (50 patients) and NMNA with High^GR + ER (74 patients) versus Low^{GR + ERα + RARα} (29 patients) mRNA expression levels. D Kaplan-Meier overall and event free survival curves for patients divided into two groups according to High^{GR + ERα + RARα} (24 patients) versus Low^{GR + ERα + RARα} (36 patients) mRNA expression levels. E mRNA expression of the neuronal differentiation markers TH, NGFR, and SCG2 between the High^{GR+ ERα + RARα} versus Low^{GR+ ERα + RARα} patient groups. Statistical analysis: t-test with *, ***, and **** indicating p < 0.05, p < 0.001, and p < 0.0001. Log-rank test was used for analysis of all Kaplan-Meier curves. p-values are shown in each plot. All data are from the SEQC cohort