Fig. 2
From: Linear DNA amplicons as a novel cancer vaccine strategy
In vivo expression of DNA amplicons. A Schematic representation of the experimental setup. BALB/c mice (3 mice/group) were injected i.m. by DNA-EP, with equimolar concentrations of plasmid DNA or DNA amplicons encoding for luciferase (50–10-5 μg/mouse). B After 1–2-7 days post DNA injection, luciferase signal was measured by performing optical imaging at IVIS. Although a significant decreased expression was detected in DNA amplicons injected mice after 7 days, no difference was measured between DNA amplicons synthetized by means of different Taq polymerase