Fig. 3
From: Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis
Leptin facilitates cell migration and invasion in NPC through EMT. a and c Wound healing assays were conducted to detect change in migratory ability in gain- or loss-of-function of leptin in TW06 cells. b and d TW06 cells with leptin overexpression or silence were subjected to Transwell assays. The representative images and the fold change of cell invasion were presented. e Expressions of EMT markers were detected by Western blotting in gain- or loss-of-function of leptin in TW06 cells. *P < 0.05, **P < 0.01, ***P < 0.001